Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472703 | 0.97 | THRB (0.48) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22426062 | 0.94 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL18194801 | 0.93 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL803176 | 0.92 | POLB (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22311497 | 0.90 | THRB (0.46) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22426054 | 0.90 | POLB (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL12321292 | 0.90 | LMNA (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10024105 | 0.89 | THRB (0.46) | THRBKDM4ENPC1LMNATP53 | |
| SCHEMBL802755 | 0.89 | POLB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL31092348 | 0.88 | THRB (0.49) | THRBKDM4ENPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-02-01 | — | — | US | disclosed |
| US-20140022473-A1 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-20140022473-A1 | Liquid-crystal display | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030350-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | THRB 3914/4885POLB 1571/4885APEX1 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.