Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334721 | 0.91 | TRPM8 (0.73) | TRPM8HTTMAPTEPHX1GAA | |
| SCHEMBL371165 | 0.89 | TRPM8 (0.70) | TRPM8HTTMAPTEPHX1TRPV1 | |
| SCHEMBL663340 | 0.88 | TRPM8 (0.69) | TRPM8MAPTALDH1A1SMN1; SMN2MALT1 | |
| SCHEMBL10072945 | 0.88 | TRPM8 (0.69) | TRPM8HTTMAPTEPHX1TRPV1 | |
| SCHEMBL2628679 | 0.88 | TRPM8 (0.69) | TRPM8MAPTALDH1A1SMN1; SMN2MALT1 | |
| SCHEMBL2628739 | 0.87 | TRPM8 (0.67) | TRPM8EPHX1GAAPOLBALDH1A1 | |
| SCHEMBL14565718 | 0.87 | TRPM8 (0.67) | TRPM8EPHX1GAAPOLBALDH1A1 | |
| SCHEMBL4883161 | 0.85 | TRPM8 (0.67) | TRPM8HTTMAPTEPHX1TRPV1 | |
| SCHEMBL661540 | 0.84 | TRPM8 (0.63) | TRPM8MAPTEPHX1TRPV1GAA | |
| SCHEMBL10073199 | 0.84 | TRPM8 (0.63) | TRPM8MAPTEPHX1TRPV1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900333-B1 | A SKIN ENGAGING MEMBER COMPRISING AT LEAST ONE THERMALLY RESILIENT SENSATE | GILLETTE CO LLC (US) | 2017-08-02 | — | — | EP | disclosed |