Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334721 | 0.89 | TRPM8 (0.73) | TRPM8HTTMAPTEPHX1ALDH1A1 | |
| SCHEMBL19189293 | 0.85 | TRPM8 (0.70) | TRPM8HTTMAPTTRPV1EPHX1 | |
| SCHEMBL371165 | 0.85 | TRPM8 (0.70) | TRPM8HTTMAPTTRPV1EPHX1 | |
| SCHEMBL2628679 | 0.84 | TRPM8 (0.69) | TRPM8MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL663340 | 0.84 | TRPM8 (0.69) | TRPM8MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10072945 | 0.84 | TRPM8 (0.69) | TRPM8HTTMAPTTRPV1EPHX1 | |
| SCHEMBL2628770 | 0.83 | TRPM8 (0.67) | TRPM8HTTTRPV1EPHX1ALDH1A1 | |
| SCHEMBL13989013 | 0.82 | TRPM8 (0.76) | TRPM8HTTMAPTTRPV1EPHX1 | |
| Acoltremon SCHEMBL23870506 | 0.81 | TRPM8 (1.00) | TRPM8TRPV1EPHX1ALDH1A1SMN1; SMN2 | |
| Acoltremon SCHEMBL16227989 | 0.81 | TRPM8 (1.00) | TRPM8TRPV1EPHX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | disclosed |
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | disclosed |
| US-20080300314-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300314-A1 | Cooling Compounds | TAS2R42, TAS2R4, TAS2R41 | TRPM8 73/4885HTT 4392/4885MAPT 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.