Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16901708 | 1.00 | SLC6A11 (0.36) | SLC6A11MCHR1PDCD1CD274HRH1 | |
| SCHEMBL16901707 | 1.00 | SLC6A11 (0.36) | SLC6A11MCHR1PDCD1CD274HRH1 | |
| SCHEMBL27144799 | 0.90 | HRH1 (0.36) | MCHR1HRH1 | |
| Hydrochloric Acid SCHEMBL27189838 | 0.89 | HRH1 (0.35) | MCHR1HRH1 | |
| Hydrochloric Acid SCHEMBL30022400 | 0.89 | HRH1 (0.35) | MCHR1HRH1 | |
| SCHEMBL27412786 | 0.88 | SLC6A11 (0.33) | SLC6A11MCHR1PDCD1CD274 | |
| SCHEMBL16901710 | 0.87 | GABRR1 (0.33) | SLC6A11 | |
| SCHEMBL27412918 | 0.85 | PDCD1 (0.34) | SLC6A11MCHR1PDCD1CD274 | |
| SCHEMBL19720564 | 0.84 | SLC6A11 (0.32) | SLC6A11MCHR1PDCD1CD274 | |
| SCHEMBL20715377 | 0.79 | SLC6A11 (0.39) | SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773635-B1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | NOVARTIS AG (CH) | 2017-08-02 | — | — | EP | disclosed |