Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20711683 | 0.92 | CYP3A4 (0.38) | SLC6A11 | |
| SCHEMBL20711677 | 0.91 | KCNQ3 (0.34) | KCNQ3KCNQ2MCHR1 | |
| SCHEMBL20711676 | 0.88 | — | — | |
| SCHEMBL19190098 | 0.85 | SLC6A11 (0.36) | PDCD1CD274SLC6A11MCHR1 | |
| SCHEMBL16901707 | 0.85 | SLC6A11 (0.36) | PDCD1CD274SLC6A11MCHR1 | |
| SCHEMBL27412786 | 0.85 | SLC6A11 (0.33) | PDCD1CD274SLC6A11MCHR1GRM2 | |
| SCHEMBL16901708 | 0.85 | SLC6A11 (0.36) | PDCD1CD274SLC6A11MCHR1 | |
| SCHEMBL19720564 | 0.81 | SLC6A11 (0.32) | PDCD1CD274SLC6A11MCHR1 | |
| SCHEMBL20711845 | 0.81 | ALDH1A1 (0.32) | SLC6A11MCHR1 | |
| SCHEMBL24091374 | 0.80 | DPP4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138206-A1 | FLUOROPYRIDOPYRIMIDINE AND FLUOROQUINAZOLINE DERIVATIES AND METHODS OF USE THEREOF | FRONTIER MEDICINES CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |