Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19720758 | 0.88 | — | — | |
| SCHEMBL16901707 | 0.84 | SLC6A11 (0.36) | SLC6A11PDCD1CD274MCHR1 | |
| SCHEMBL27412786 | 0.84 | SLC6A11 (0.33) | SLC6A11PDCD1CD274MCHR1 | |
| SCHEMBL19190098 | 0.84 | SLC6A11 (0.36) | SLC6A11PDCD1CD274MCHR1 | |
| SCHEMBL16901708 | 0.84 | SLC6A11 (0.36) | SLC6A11PDCD1CD274MCHR1 | |
| SCHEMBL27412918 | 0.81 | PDCD1 (0.34) | SLC6A11PDCD1CD274MCHR1 | |
| SCHEMBL19720551 | 0.81 | CYP1A2 (0.34) | — | |
| SCHEMBL19720549 | 0.79 | FGFR2 (0.31) | — | |
| SCHEMBL19720522 | 0.78 | — | — | |
| SCHEMBL20715377 | 0.75 | SLC6A11 (0.39) | SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257848-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING EGFR ACTIVITY | Novartis AG (CH) | 2017-12-20 | — | — | EP | disclosed |