SCHEMBL19195

SCHEMBL19195

Cn1nc(C(=N)NO)cc1C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.40
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.37
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC7 Q8WUI4 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC9 Q9UKV0 2/20 0.35
HDAC5 Q9UQL6 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27787731 0.75 PKM (0.51) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL16690902 0.74 PKM (0.50) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL18510 0.74 PKM (0.54) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL31459702 0.73 ALDH1A1 (0.50) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL24571057 0.72 PKM (0.49) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL17940 0.72 PKM (0.49) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL19196 0.70 PKM (0.43) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL12474101 0.70 HDAC3 (0.47) NPC1ALDH1A1RAB9AHDAC3HDAC4
SCHEMBL18120300 0.70 PKM (0.47) PKMNPC1ALDH1A1RAB9AMAPT
SCHEMBL28057286 0.69 PKM (0.49) PKMNPC1ALDH1A1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012025460-A1 OXADIAZOLINONE DERIVATIVES AND USE THEREOF IN PEST CONTROL BAYER CROPSCIENCE AG (DE) 2012-03-01 WO disclosed