Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230844 | 0.86 | TRPM4 (0.52) | TRPM4NQO2PTPN22CYP1A2ALOX5 | |
| SCHEMBL8338477 | 0.83 | CA2 (0.42) | TRPM4NQO2CYP1A2ALOX5ALDH1A1 | |
| SCHEMBL17030754 | 0.81 | TRPM4 (0.47) | TRPM4NQO2MPLPTPN22CYP1A2 | |
| SCHEMBL24859351 | 0.79 | ALDH1A1 (0.44) | TRPM4NQO2CYP1A2ALOX5ALDH1A1 | |
| SCHEMBL9838388 | 0.78 | GPR35 (0.58) | MPLCYP1A2HTTALDH1A1TSHR | |
| Boric Acid SCHEMBL28651574 | 0.76 | ALDH1A1 (0.41) | TRPM4NQO2CYP1A2ALOX5ALDH1A1 | |
| SCHEMBL2221239 | 0.76 | PTPN22 (0.54) | PTPN22CYP1A2ALDH1A1TSHRTDP1 | |
| SCHEMBL11230863 | 0.76 | CA2 (0.42) | TRPM4NQO2PTPN22CYP1A2ALDH1A1 | |
| SCHEMBL8659860 | 0.76 | CYP1A2 (0.42) | TRPM4NQO2PTPN22CYP1A2LMNA | |
| Ethane SCHEMBL28303517 | 0.75 | TRPM4 (0.58) | TRPM4NQO2MPLPTPN22CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739223-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-11352512-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | TRPM4 3661/4885NQO2 2904/4885MPL 2902/4885 |
| US-11352512-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | TRPM4 3661/4885NQO2 2904/4885MPL 2902/4885 |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | TRPM4 3661/4885NQO2 2904/4885MPL 2902/4885 |
| US-11739223-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | TRPM4 3661/4885NQO2 2904/4885MPL 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.