Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341228 | 0.84 | CA1 (0.35) | CA1CA2POLBGAAGFER | |
| SCHEMBL6542714 | 0.81 | ALDH1A1 (0.39) | CA1CA2POLBGAAGFER | |
| SCHEMBL19972035 | 0.79 | CA1 (0.48) | CA1CA2GAAGABRA1GABRB1 | |
| SCHEMBL19971996 | 0.79 | — | — | |
| SCHEMBL19972017 | 0.79 | P2RX3 (0.30) | — | |
| SCHEMBL19972059 | 0.79 | CA1 (0.43) | CA1CA2GAAGABRA1GABRB1 | |
| SCHEMBL8976031 | 0.78 | GAA (0.38) | CA1CA2POLBGAAGFER | |
| SCHEMBL19972003 | 0.76 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL4634575 | 0.75 | CA1 (0.39) | CA1CA2GABRA1GABRB1GABRB2 | |
| SCHEMBL9913258 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132511-A1 | BENZIMIDAZOLE COMPOUNDS, USE AS INHIBITORS OF WNT SIGNALING PATHWAY IN CANCERS, AND METHODS FOR PREPARATION THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2017-08-03 | — | — | WO | disclosed |