Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542719 | 0.82 | POLB (0.40) | GAAPOLBGFER | |
| SCHEMBL10339164 | 0.81 | GAA (0.38) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL3691524 | 0.81 | GAA (0.38) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL19197818 | 0.78 | CA1 (0.32) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL25162202 | 0.76 | CYP3A4 (0.40) | GAAPOLBGFERALDH1A1ALOX12 | |
| SCHEMBL6542714 | 0.74 | ALDH1A1 (0.39) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL7537233 | 0.74 | POLB (0.41) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL23153641 | 0.74 | GABRA1 (0.43) | GAAPOLBGFERCA1CA2 | |
| SCHEMBL29036816 | 0.74 | POLB (0.42) | GAAPOLBGFER | |
| SCHEMBL18135464 | 0.73 | GAA (0.46) | GAAPOLBGFERCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705863-A1 | Two stage melt polymerization process for making polybenzimidazoles | HOECHST CELANESE CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |
| US-4895928-A | AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0263593-A2 | Melt-processable polymeric materials based on 5-t-butalisophthalic acid | AMOCO CORPORATION (US) | 1988-04-13 | — | — | EP | disclosed |
| US-4717764-A | Two stage melt polymerization process for making polymers containing aromatic amide groups | CELANESE CORPORATION (US) | 1988-01-05 | — | — | US | disclosed |