Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19197994 | 0.97 | SIGMAR1 (0.37) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL19197827 | 0.94 | SIGMAR1 (0.39) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL19197984 | 0.89 | SIGMAR1 (0.40) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL19198230 | 0.87 | CHRM2 (0.35) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| SCHEMBL17102940 | 0.82 | SIGMAR1 (0.50) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| Ethylenediamine SCHEMBL19197826 | 0.81 | SIGMAR1 (0.43) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| Water SCHEMBL28622482 | 0.81 | SIGMAR1 (0.48) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| Hydrochloric Acid SCHEMBL28600382 | 0.81 | SIGMAR1 (0.48) | SIGMAR1CYP3A4LMNACYP1A2CYP2D6 | |
| Phosphoric Acid SCHEMBL19197822 | 0.80 | SIGMAR1 (0.36) | SIGMAR1CHRM2CHRM1CHRM4CHRM3 | |
| Putrescine SCHEMBL19198229 | 0.80 | GSR (0.44) | SIGMAR1LMNACYP1A2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | claimed |
| CN-112533935-A | Platinum compound phosphate and preparation method thereof | 北京硕佰医药科技有限责任公司 | 2021-03-19 | — | — | CN | disclosed |
| US-9725477-B2 | Platinum compounds of malonic acid derivative having leaving group containing amino or alkylamino | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2017-08-08 | — | — | US | disclosed |