SCHEMBL191996

SCHEMBL191996

COc1cc(N)cc(OC)c1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.59
MAPT P10636 3/20 0.56
CYP3A4 P08684 1/20 0.56
CA9 Q16790 1/20 0.56
CYP19A1 P11511 3/20 0.55
NQO2 P16083 1/20 0.55
PTGS2 P35354 1/20 0.52
HTR2A P28223 1/20 0.52
HTR2C P28335 1/20 0.52
HTR2B P41595 1/20 0.52
PTAFR P25105 2/20 0.48
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47
TUBA1B P68363 1/20 0.47
TUBA4A P68366 1/20 0.47
TUBB4B P68371 1/20 0.47
TUBB3 Q13509 1/20 0.47
TUBB2A Q13885 1/20 0.47
TUBB8 Q3ZCM7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4381078 0.97 ACHE (0.56) ACHEMAPTCYP3A4CA9CYP19A1
Ammonia Solution, Strong SCHEMBL4946565 0.97 ACHE (0.56) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL909800 0.89 ACHE (0.48) ACHEMAPTCYP3A4CA9CYP19A1
Alcohol SCHEMBL9525249 0.89 PTGS2 (0.54) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL21264353 0.87 MAPT (0.47) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL2529901 0.87 ACHE (0.46) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL12903992 0.85 ACHE (0.44) ACHEMAPTCYP3A4CA9CYP19A1
Hydrochloric Acid SCHEMBL8521226 0.85 MAPT (0.46) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL6977792 0.85 ACHE (0.50) ACHEMAPTCYP3A4CA9CYP19A1
SCHEMBL1766178 0.84 HTR2A (0.44) ACHEMAPTCYP3A4CA9CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2656 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12322545-B2 Electrodes for electrochemical capacitors based on surface-modified carbon EEXION ENERGY LTD. (IL) 2025-06-03 US claimed
CN-119977832-A Benzoyl hydrazine antineoplastic compound and preparation method and application thereof 江苏海洋大学 2025-05-13 CN claimed
CN-116947791-B Furanamide antitumor compound and preparation method and application thereof 北京中医药大学 2025-04-25 CN claimed
CN-119751460-A Triazolopyrimidine antitumor compound and preparation method and application thereof 江苏海洋大学 2025-04-04 CN claimed
CN-118772112-B PROTAC medicine molecule targeting Fam20C as well as preparation method and application thereof 西南交通大学 2025-04-01 CN claimed
CN-119638984-A Polyaramid hole transport material, synthesis method thereof and perovskite solar cell 浙江大学 2025-03-18 CN claimed
WO-2025016234-A1 N-ORTHO-AMINOBENZOYLTRYPTAMINE DERIVATIVE, PREPARATION METHOD, COMPOSITION, AND USE 南华大学附属第一医院 2025-01-23 WO claimed
CN-118772112-A PROTAC medicine molecule targeting Fam20C as well as preparation method and application thereof 西南交通大学 2024-10-15 CN claimed
US-12097271-B2 Dental composition DENTSPLY SIRONA INC. (US) 2024-09-24 US claimed
CN-118496143-A N-anthranilamide derivatives, preparation method, composition and application 南华大学附属第一医院 2024-08-16 CN claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
WO-2000027394-A1 ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE UNIVERSITY COLLEGE LONDON (GB) 2000-05-18 WO claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-1999051228-A1 METHODS FOR INHIBITING MRP1 ELI LILLY AND COMPANY (US) 1999-10-14 WO claimed
EP-0863877-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INST (US) 1999-07-21 EP claimed
US-5874443-A BIOSYNTHESIS TREGA BIOSCIENCES, INC. (US) 1999-02-23 US claimed
EP-0863877-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1998-09-16 EP claimed
WO-1997016428-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) 1997-05-09 WO claimed
WO-1992017478-A1 5-ALKYL-6-[[AMINO]METHYL]PYRIDO[2,3-d]PYRIMIDINE DERIVATIVES AND METHODS OF PREPARING AND USING THESE DERIVATIVES DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) 1992-10-15 WO claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed