Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 4/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 3/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19198986 | 1.00 | SIGMAR1 (0.39) | SIGMAR1LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL19250240 | 0.90 | LMNA (0.38) | SIGMAR1LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL20975784 | 0.82 | CHRNA7 (0.36) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL25259435 | 0.78 | CHRNA7 (0.39) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL10216998 | 0.75 | LMNA (0.34) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL26798272 | 0.75 | LMNA (0.34) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL16512349 | 0.73 | CHRNA7 (0.38) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL2304454 | 0.73 | CHRNA7 (0.38) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL16512320 | 0.73 | CHRNA7 (0.38) | LMNACHRM2ADRA2ACYP2D6TSHR | |
| SCHEMBL2304458 | 0.73 | CHRNA7 (0.38) | LMNACHRM2ADRA2ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217974-A1 | HEPATITIS B ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217974-A1 | HEPATITIS B ANTIVIRAL AGENTS | HAVCR2, ZC3HAV1, SLC10A1 | SIGMAR1 1256/4885LMNA 1313/4885CHRM2 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.