Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16364352 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL2101753 | 1.00 | — | — | |
| SCHEMBL16572707 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL14117903 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL17573237 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL2099026 | 1.00 | — | — | |
| SCHEMBL446418 | 1.00 | — | — | |
| SCHEMBL15929564 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 | |
| SCHEMBL20636071 | 1.00 | — | — | |
| SCHEMBL28416123 | 1.00 | TSHR (0.45) | TSHRTDP1CYP2C9CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108661-A1 | ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE | Idemitsu Kosan Co.,Ltd. (JP) | 2022-12-28 | — | — | EP | disclosed |
| US-20220160995-A1 | METHODS AND DEVICES FOR MODULATION OF INTEGRATED NEURAL NETWORKS TO INFLUENCE COMPOSITE SENSORY PROCESSES | IST, LLC | 2022-05-26 | — | — | US | disclosed |
| US-10793304-B2 | High-flow, low-velocity gas flushing system for reducing and monitoring oxygen content in packaged produce containers | DOLE FRESH VEGETABLES, INC. (US) | 2020-10-06 | — | — | US | disclosed |
| WO-2019243533-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2019-12-26 | — | — | WO | disclosed |
| US-20190151483-A1 | METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2019-05-23 | — | — | US | disclosed |
| US-20190071441-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-03-07 | — | — | US | disclosed |
| US-10174025-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-08 | — | — | US | disclosed |
| WO-2018071622-A1 | 3-SULFONYL-5-AMINOPYRIDINE-2,4-DIOL APJ AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-19 | — | — | WO | disclosed |
| US-20180099964-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-12 | — | — | US | disclosed |
| WO-2018022603-A1 | METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2018-02-01 | — | — | WO | disclosed |
| US-9879009-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-01-30 | — | — | US | disclosed |
| US-9777000-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2017-10-03 | — | — | US | disclosed |
| US-9775845-B2 | Carbazole-containing sulfonamides as cryptochrome modulators | RESET THERAPEUTICS, INC. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20170217958-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217958-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | CYP3A7, CYP2C19, CYP3A5 | TSHR 1311/4885TDP1 3034/4885CYP2C9 9/4885 |
| US-10174025-B2 | Pyrazole derivative manufacturing method | CYP3A5, CYP3A7, CYP3A4 | TSHR 1457/4885TDP1 2251/4885CYP2C9 7/4885 |
| US-20180099964-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | CYP3A5, CYP3A7, CYP3A4 | TSHR 1457/4885TDP1 2251/4885CYP2C9 7/4885 |
| US-20190071441-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | CYP3A5, CYP3A7, CYP3A4 | TSHR 1457/4885TDP1 2251/4885CYP2C9 7/4885 |
| US-20190151483-A1 | METHODS OF MAKING 18F-LABELED PRECURSORS AND PEPTIDES, LABELED C-MET BINDING PEPTIDES, AND METHODS OF USE THEREOF | MET, MYCBP, METTL14 | TSHR 333/4885TDP1 4247/4885CYP2C9 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.