SCHEMBL1920076

SCHEMBL1920076

O=C(O)C1CC2CC1CC2SC1CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4384475 0.69 GABRR1 (0.30)
SCHEMBL6161898 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL21705290 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL6382754 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL75505 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL24004713 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL900095 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL16898630 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL5431682 0.68 KDM4E (0.61) KDM4ELMNAEPHX2
SCHEMBL5058845 0.68 KDM4E (0.61) KDM4ELMNAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US claimed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO claimed
EP-2326744-B1 METAL COMPOSITIONS AND METHODS OF MAKING SAME PRYOG LLC (US) 2022-06-01 EP disclosed
US-9499646-B2 Negative resist composition, method of forming resist pattern and complex TOKYO OHKA KOGYO CO., LTD. (JP) 2016-11-22 US disclosed
US-20160259244-A1 NEGATIVE RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN AND COMPLEX TOKYO OHKA KOGYO CO LTD (JP) 2016-09-08 US disclosed
US-9366960-B2 Negative resist composition, method of forming resist pattern, and complex TOKYO OHA KOGYO CO., LTD. (JP) 2016-06-14 US disclosed
US-20150192851-A1 NEGATIVE RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND COMPLEX TOKYO OHKA KOGYO CO, LTD. (JP) 2015-07-09 US disclosed
US-8802346-B2 Metal compositions and methods of making same PRYOG, LLC (US) 2014-08-12 US disclosed
US-8709705-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2014-04-29 US disclosed
US-20120315451-A1 Metal-Containing Compositions and Method of Making Same PRYOG LLC 2012-12-13 US disclosed
US-20110184139-A1 METAL COMPOSITIONS AND METHODS OF MAKING SAME PRYOG, LLC 2011-07-28 US disclosed
EP-2326744-A1 METAL COMPOSITIONS AND METHODS OF MAKING SAME Pryog LLC (US) 2011-06-01 EP disclosed
WO-2010059174-A1 METAL COMPOSITIONS AND METHODS OF MAKING SAME PRYOG, LLC (US) 2010-05-27 WO disclosed
US-7629424-B2 Metal-containing compositions and method of making same PRYOG, LLC (US) 2009-12-08 US disclosed
US-20080015278-A1 Metal-Containing Compositions and Method of Making Same PRYOG, LLC 2008-01-17 US disclosed
WO-2007070092-A2 METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME PRYOG, LLC (US) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160259244-A1 NEGATIVE RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN AND COMPLEX ACTN4, CHD4, H1-4 KDM4E 1729/4885LMNA 1515/4885EPHX2 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.