Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYH2 | Q9UKX2 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | MYH9 | P35579 | 1/20 | 0.62 |
| ▸ | MYH10 | P35580 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HBB | P68871 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29695613 | 1.00 | MYH2 (1.00) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL29695618 | 1.00 | MYH2 (1.00) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL29695657 | 1.00 | MYH2 (1.00) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL21067621 | 0.83 | MEN1 (0.83) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL18214930 | 0.82 | KMT2A (0.74) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL21067295 | 0.82 | KMT2A (0.74) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL25247212 | 0.80 | MYH2 (0.67) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL23917036 | 0.80 | MEN1 (0.77) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL23909337 | 0.80 | MEN1 (0.70) | MYH2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL23909334 | 0.80 | MEN1 (0.70) | MYH2MAPTMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858357-B2 | Water-soluble myosin 2 inhibitors for the treatment of neurological, neuropathic or psychiatric diseases | PARIS SCIENCES ET LETTRES-QUARTIER LATIN (FR) | 2020-12-08 | — | — | US | disclosed |
| US-20190084979-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | PARIS SCIENCES ET LETTRES (FR) | 2019-03-21 | — | — | US | disclosed |
| WO-2017129782-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084979-A1 | WATER-SOLUBLE MYOSIN 2 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL, NEUROPATHIC OR PSYCHIATRIC DISEASES | MYH2, MYO1B, MYO1F | MYH2 1/4885MAPT 122/4885MEN1 2772/4885 |
| US-10858357-B2 | Water-soluble myosin 2 inhibitors for the treatment of neurological, neuropathic or psychiatric diseases | MYH2, MYO1B, MYO1F | MYH2 1/4885MAPT 122/4885MEN1 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.