Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 13/20 | 0.75 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19201155 | 0.86 | S1PR5 (1.00) | S1PR5 | |
| SCHEMBL19201119 | 0.85 | S1PR5 (0.72) | S1PR5HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL20679829 | 0.79 | S1PR5 (0.89) | S1PR5 | |
| SCHEMBL29332485 | 0.77 | S1PR5 (0.60) | S1PR5HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL2314388 | 0.75 | MEN1 (0.66) | ADRA1A | |
| SCHEMBL22129565 | 0.74 | TDP1 (0.61) | — | |
| SCHEMBL30900805 | 0.74 | TDP1 (0.61) | — | |
| SCHEMBL20573749 | 0.73 | S1PR5 (0.58) | S1PR5SIGMAR1 | |
| SCHEMBL8687907 | 0.73 | HTR7 (0.76) | HTR1ADRD2HTR2ASLC6A4HTR7 | |
| SCHEMBL1616841 | 0.73 | TDP1 (0.59) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017131149-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | 小野薬品工業株式会社 | 2017-08-03 | — | — | WO | disclosed |