Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 12/20 | 0.76 |
| ▸ | HTR1A | P08908 | 10/20 | 0.76 |
| ▸ | DRD2 | P14416 | 7/20 | 0.76 |
| ▸ | DRD3 | P35462 | 7/20 | 0.76 |
| ▸ | HTR2B | P41595 | 7/20 | 0.76 |
| ▸ | HTR2A | P28223 | 6/20 | 0.76 |
| ▸ | HRH1 | P35367 | 6/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3887340 | 0.98 | HTR7 (0.74) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL17598257 | 0.95 | HDAC3 (0.71) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL3477555 | 0.90 | HDAC3 (0.70) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL4229925 | 0.88 | HTR7 (0.73) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL20358752 | 0.87 | HTR1A (1.00) | HTR7HTR1ADRD2DRD3HTR2B | |
| Hydrochloric Acid SCHEMBL4222979 | 0.86 | HTR7 (0.71) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL16993484 | 0.83 | HDAC3 (0.55) | HTR7HTR1ADRD2DRD3HTR2B | |
| Fumaric Acid SCHEMBL4232353 | 0.83 | HTR7 (0.66) | HTR7HTR1ADRD2DRD3HTR2B | |
| SCHEMBL4225894 | 0.83 | HDAC3 (0.71) | HTR7HTR1ADRD2DRD3HTR2B | |
| Acetic Acid SCHEMBL6524435 | 0.82 | DRD3 (0.64) | HTR7HTR1ADRD2DRD3HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789434-A | ACID, ESTER OR AMIDE DERIVATIVES AS ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS AND REDUCTION OF CARTILAGE DETERIORATION | BAYER CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |