Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772839 | 0.76 | ALDH1A1 (0.36) | LMNA | |
| SCHEMBL27637969 | 0.74 | LMNA (0.38) | MCL1LMNA | |
| SCHEMBL12917023 | 0.73 | LMNA (0.41) | MCL1LMNA | |
| SCHEMBL3582797 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL15827325 | 0.73 | CA12 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL15945375 | 0.72 | ALDH1A1 (0.44) | MCL1LMNA | |
| SCHEMBL24845988 | 0.71 | REN (0.35) | LMNA | |
| SCHEMBL3989465 | 0.70 | — | — | |
| SCHEMBL14048777 | 0.70 | — | — | |
| SCHEMBL8699794 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132432-A1 | BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |