SCHEMBL19201531

SCHEMBL19201531

O=C(Nc1ccc(Br)cc1)NN1C(=O)NC2(CCCCCC2)C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 20/20 1.00
AKR1B1 P15121 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14935681 1.00 FPR2 (1.00) FPR2AKR1B1
SCHEMBL14935439 0.99 FPR2 (1.00) FPR2AKR1B1
SCHEMBL14951275 0.88 FPR2 (1.00) FPR2AKR1B1
SCHEMBL14938341 0.85 FPR2 (0.74) FPR2AKR1B1
SCHEMBL14935374 0.83 FPR2 (0.73) FPR2
SCHEMBL14935503 0.82 FPR2 (0.74) FPR2
SCHEMBL14945852 0.81 FPR2 (0.69) FPR2
SCHEMBL14935394 0.81 FPR2 (0.67) FPR2AKR1B1
SCHEMBL14935314 0.79 FPR2 (0.67) FPR2
SCHEMBL16008139 0.78 FPR2 (1.00) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10434112-B2 Use of agonists of formyl peptide receptor 2 for treating dermatological diseases ALLERGAN, INC. (US) 2019-10-08 US disclosed
US-20170216326-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. 2017-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170216326-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES FPR2, FPR1, FPR3 FPR2 1/4885AKR1B1 1894/4885
US-10434112-B2 Use of agonists of formyl peptide receptor 2 for treating dermatological diseases FPR2, FPR1, FPR3 FPR2 1/4885AKR1B1 1894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.