Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340063 | 0.85 | TRPA1 (0.43) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL6355043 | 0.83 | TRPA1 (0.44) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL5676618 | 0.80 | TRPA1 (0.52) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL30159693 | 0.80 | TRPA1 (0.52) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL28664564 | 0.80 | TRPA1 (0.52) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL15847007 | 0.78 | TRPM4 (0.45) | TRPA1CYP1A2CYP2A6DAOTP53 | |
| SCHEMBL19202403 | 0.77 | LDHA (0.54) | CYP1A2DAODDOHSD17B10ALDH1A1 | |
| SCHEMBL19202406 | 0.77 | LDHA (0.58) | CYP1A2DAODDOHSD17B10ALDH1A1 | |
| SCHEMBL29291168 | 0.77 | CYP2A6 (0.45) | TRPA1CYP1A2CYP2A6TP53TDP1 | |
| SCHEMBL21920117 | 0.77 | CYP1A2 (0.48) | TRPA1CYP1A2CYP2A6TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| WO-2017132463-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | TRPA1 2167/4885CYP1A2 2409/4885CYP2A6 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.