Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19202200 | 0.85 | TRPA1 (0.44) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL30277948 | 0.83 | CYP1A2 (0.45) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL13021181 | 0.83 | CYP1A2 (0.45) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL5676618 | 0.78 | TRPA1 (0.52) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL28664564 | 0.78 | TRPA1 (0.52) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL30159693 | 0.78 | TRPA1 (0.52) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL23686781 | 0.77 | ACHE (0.44) | CYP2A6CYP1A2TP53TDP1ACHE | |
| SCHEMBL15847007 | 0.77 | TRPM4 (0.45) | TRPA1CYP2A6CYP1A2DAODDO | |
| SCHEMBL9233004 | 0.77 | TRPM4 (0.61) | CYP2A6CYP1A2HSD17B10ALDH1A1TRPM4 | |
| SCHEMBL29771816 | 0.77 | TRPM4 (0.61) | CYP2A6CYP1A2HSD17B10ALDH1A1TRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230170-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
| WO-2004014384-A2 | CYCLIC COMPOUNDS CONTAINING ZINC BINDING GROUPS AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0415422-A2 | Method for forming images | FUJI PHOTO FILM CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230170-A1 | KRAS G12C INHIBITORS | KRAS, NRAS, HRAS | TRPA1 4579/4885CYP2A6 3884/4885CYP1A2 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.