SCHEMBL19202207

SCHEMBL19202207

Oc1cc2c(I)cncc2c(O)c1O

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.31
SELL P14151 1/20 0.31
SELP P16109 1/20 0.31
SELE P16581 1/20 0.31
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19202477 0.75 SELL (0.41) SELLSELPSELEBCL2MCL1
SCHEMBL19195705 0.71 ALDH1A1 (0.40) SELLSELPSELE
Iopydone SCHEMBL666662 0.69
SCHEMBL19202206 0.68 LMNA (0.38) TTRMCL1
SCHEMBL22966139 0.68 SELL (0.42) SELLSELPSELEBCL2MCL1
SCHEMBL31551783 0.64 ESR1 (0.34)
SCHEMBL9827753 0.62 DAO (0.44)
SCHEMBL19730501 0.61 TTR (0.50) TTRSELLSELPSELEBCL2
SCHEMBL3068434 0.61 CYP11B1 (0.46) MCL1
SCHEMBL12862696 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017132463-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2017-08-03 WO disclosed