Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.40 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19202477 | 0.75 | SELL (0.41) | ALDH1A1MAPTKDM4ECA2CA1 | |
| SCHEMBL19195688 | 0.72 | CA2 (0.54) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL19202207 | 0.71 | TTR (0.31) | SELLSELPSELE | |
| SCHEMBL22096882 | 0.68 | CA2 (0.38) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL19193402 | 0.66 | ALDH1A1 (0.62) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL29316522 | 0.66 | ALDH1A1 (0.42) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL23179826 | 0.64 | PRKCB (0.33) | — | |
| SCHEMBL22966139 | 0.64 | SELL (0.42) | ALDH1A1ALOX15SMN1; SMN2MAPTKDM4E | |
| SCHEMBL6933390 | 0.63 | ALDH1A1 (0.56) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL1374664 | 0.63 | ALDH1A1 (0.77) | ALDH1A1ALOX15SMN1; SMN2CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739223-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-11739223-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2023-08-29 | — | — | US | disclosed |
| US-11352512-B2 | Surface primer compositions and methods of use | ENVISTA (US) | 2022-06-07 | — | — | US | disclosed |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ENVISTA (US) | 2020-11-05 | — | — | US | disclosed |
| US-10696698-B2 | Surface primer compositions and methods of use | ORMCO CORPORATION | 2020-06-30 | — | — | US | disclosed |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696698-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | ALDH1A1 1177/4885ALOX15 3081/4885SMN1; SMN2 2174/4885 |
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | ALDH1A1 1177/4885ALOX15 3081/4885SMN1; SMN2 2174/4885 |
| US-11352512-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | ALDH1A1 1177/4885ALOX15 3081/4885SMN1; SMN2 2174/4885 |
| US-20200347247-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | ALDH1A1 1177/4885ALOX15 3081/4885SMN1; SMN2 2174/4885 |
| US-11739223-B2 | Surface primer compositions and methods of use | SP1, GPER1, GRIN1 | ALDH1A1 1177/4885ALOX15 3081/4885SMN1; SMN2 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.