SCHEMBL1920223

SCHEMBL1920223

O=[C]c1ccc2ccc3ccccc3c2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HSD17B10 Q99714 3/20 0.56
CYP1B1 Q16678 2/20 0.56
HIF1A Q16665 1/20 0.56
CYP2A6 P11509 1/20 0.52
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP1A2 P05177 3/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CYP1A1 P04798 1/20 0.48
HPRT1 P00492 4/20 0.48
PAX8 Q06710 1/20 0.45
CASP3 P42574 1/20 0.43
GFER P55789 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
HPGD P15428 2/20 0.42
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920437 0.89 CYP1A2 (0.61) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL69325 0.79 CES2 (0.43) ALDH1A1HSD17B10CYP1B1CYP2A6TDP1
SCHEMBL1343465 0.78 CA1 (0.69) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL29245731 0.78 CYP1B1 (0.56) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL9098387 0.78 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1TSHRTDP1
SCHEMBL476027 0.78 CTDSP1 (0.53) ALDH1A1HSD17B10TSHRTDP1CYP1A2
SCHEMBL5381544 0.78 MEN1 (0.39) CYP1B1CYP1A2CA1CA2CYP1A1
SCHEMBL1921032 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL3632654 0.75 CA1 (0.65) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL9671450 0.75 GABRA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813979-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-09-29 CN disclosed
CN-112839988-B Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2023-06-06 CN disclosed
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-12-23 US disclosed
EP-3858909-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF ADEKA CORPORATION (JP) 2021-08-04 EP disclosed
CN-112839988-A Nucleating agent, synthetic resin composition containing same, and molded article thereof 株式会社ADEKA 2021-05-25 CN disclosed
WO-2020067144-A1 NUCLEATING AGNET, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF 株式会社ADEKA 2020-04-02 WO disclosed
US-8394974-B2 Process for producing optically active chromene oxide compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-03-12 US disclosed
EP-1718629-B1 Benzopyran compounds useful for the treatment of arrhytmia NISSAN CHEMICAL IND LTD (JP) 2012-12-26 EP disclosed
US-7964623-B2 Tricyclic benzopyrane compound NISSAN CHEMICAL INDUSTRIES LTD. (JP) 2011-06-21 US disclosed
EP-1590491-B1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF SE (DE) 2011-06-01 EP disclosed
US-20060101583-A1 Adducts based on cyclic compounds and the use thereof as tanning agents and curing agents BASF AKTIENGESELLSCHAFT (DE) 2006-05-18 US disclosed
US-20060053564-A1 Tanning agents and preservatives BASF AKTIENGESELLSCHAFT (DE) 2006-03-16 US disclosed
US-20050282730-A1 Thrombopoetin receptor activator and process for producing the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-12-22 US disclosed
EP-1590491-A1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF Aktiengesellschaft (DE) 2005-11-02 EP disclosed
EP-1590492-A1 TANNING AGENTS AND PRESERVATIVES BASF AKTIENGESELLSCHAFT (DE) 2005-11-02 EP disclosed
WO-2005090357-A1 TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-09-29 WO disclosed
EP-1552828-A1 THROMBOPOETIN RECEPTOR ACTIVATOR AND PROCESS FOR PRODUCING THE SAME Nissan Chemical Industries, Ltd. (JP) 2005-07-13 EP disclosed
WO-2005031007-A1 METHOD FOR THE PRODUCTION OF LEATHER AND SEMIFINISHED PRODUCTS, AND FORMULATIONS THAT ARE SUITABLE THEREFOR BASF AKTIENGESELLSCHAFT (DE) 2005-04-07 WO disclosed
WO-2004067782-A1 TANNING AGENTS AND PRESERVATIVES BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 WO disclosed
WO-2004067781-A1 ADDUCTS BASED ON CYCLIC COMPOUNDS AND THE USE THEREOF AS TANNING AGENTS AND CURING AGENTS BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210395209-A1 NUCLEATING AGENT, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF NOC2L, RIF1, NAP1L1 ALDH1A1 2699/4885HSD17B10 3823/4885CYP1B1 2753/4885
US-20050282730-A1 Thrombopoetin receptor activator and process for producing the same PDGFRA, PTAFR, TBXA2R ALDH1A1 2034/4885HSD17B10 1809/4885CYP1B1 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.