Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 6/20 | 0.58 |
| ▸ | LDHB | P07195 | 6/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19202406 | 0.86 | LDHA (0.58) | LDHALDHBALBDHODHCSNK2A1 | |
| SCHEMBL19202491 | 0.86 | LDHA (0.54) | LDHALDHBALBDHODHCSNK2A1 | |
| SCHEMBL24116339 | 0.82 | CA12 (0.42) | LDHALDHBALBDHODHGLRA3 | |
| SCHEMBL19203353 | 0.81 | CSNK2A1 (0.52) | LDHALDHBALBDHODHCSNK2A1 | |
| SCHEMBL11777447 | 0.79 | GLRA3 (0.50) | LDHALDHBALBDHODHGLRA3 | |
| SCHEMBL6355043 | 0.77 | TRPA1 (0.44) | LDHALDHBALBCSNK2A1DAO | |
| SCHEMBL10111010 | 0.77 | CYP1A2 (0.53) | LDHALDHBALBDHODHCSNK2A1 | |
| SCHEMBL88986 | 0.77 | CYP1A2 (0.68) | LDHADHODHPOLBMEN1KMT2A | |
| SCHEMBL29779946 | 0.77 | CYP1A2 (0.68) | LDHADHODHPOLBMEN1KMT2A | |
| SCHEMBL931067 | 0.76 | LDHA (0.50) | LDHALDHBALBDHODHCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ORMCO CORPORATION | 2017-08-03 | — | — | US | disclosed |
| WO-2017132463-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217999-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | SP1, GPER1, GRIN1 | LDHA 2656/4885LDHB 2298/4885ALB 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.