SCHEMBL10111010

SCHEMBL10111010

Cc1ccc2c(C(=O)O)c3cc(C)ccc3cc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.53
ALDH1A1 P00352 4/20 0.53
KDM4E B2RXH2 3/20 0.53
HPGD P15428 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
CYP2C19 P33261 1/20 0.53
LDHA P00338 3/20 0.51
LDHB P07195 3/20 0.51
ALB P02768 1/20 0.47
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
DHODH Q02127 3/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 1/20 0.42
CYP2A6 P11509 3/20 0.41
PIN1 Q13526 1/20 0.41
MPL P40238 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11634862 0.88 ALDH1A1 (0.72) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL931068 0.84 ALDH1A1 (0.52) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL30623601 0.82 ALDH1A1 (0.47) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL19203353 0.82 CSNK2A1 (0.52) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL25487733 0.81 LDHA (0.46) CYP1A2ALDH1A1KDM4EHPGDMEN1
Ethylene SCHEMBL28494344 0.81 ALDH1A1 (0.49) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL7144236 0.78 LDHA (0.50) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL931067 0.77 LDHA (0.50) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL7144235 0.77 ALDH1A1 (0.50) CYP1A2ALDH1A1KDM4EHPGDMEN1
SCHEMBL19202293 0.77 LDHA (0.58) CYP1A2ALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9536633-B2 Metallic composite and composition thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-03 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032121-A1 METALLIC COMPOSITE AND COMPOSITION THEREOF CDH1, EPCAM, CD4 CYP1A2 2849/4885ALDH1A1 932/4885KDM4E 3592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.