Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 8/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322742 | 1.00 | SIRT5 (0.37) | SIRT5C3AR1GLP1R | |
| SCHEMBL24860409 | 0.83 | C3AR1 (0.38) | SIRT5C3AR1 | |
| SCHEMBL19203408 | 0.81 | SIRT5 (0.41) | SIRT5C3AR1 | |
| SCHEMBL19203552 | 0.77 | SIRT5 (0.40) | SIRT5C3AR1GLP1R | |
| SCHEMBL21322470 | 0.76 | SIRT5 (0.32) | SIRT5C3AR1 | |
| SCHEMBL17381414 | 0.75 | SIRT5 (0.39) | SIRT5C3AR1GLP1R | |
| SCHEMBL20793387 | 0.74 | C3AR1 (0.41) | SIRT5C3AR1 | |
| SCHEMBL20375713 | 0.74 | C3AR1 (0.41) | SIRT5C3AR1 | |
| SCHEMBL18051173 | 0.74 | C3AR1 (0.41) | SIRT5C3AR1 | |
| SCHEMBL21322625 | 0.74 | C3AR1 (0.32) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |