Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122900 | 0.85 | SIRT5 (0.36) | — | |
| SCHEMBL21534501 | 0.83 | SIRT5 (0.33) | — | |
| SCHEMBL19170464 | 0.81 | SIRT5 (0.31) | — | |
| SCHEMBL19203576 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19170723 | 0.79 | SMN1; SMN2 (0.34) | MEN1KMT2A | |
| SCHEMBL19203517 | 0.77 | HPGD (0.33) | MEN1KMT2A | |
| SCHEMBL12197747 | 0.76 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL18532465 | 0.76 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22202997 | 0.76 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL13056639 | 0.76 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017132173-A1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMACEUTICALS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |