Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21210814 | 0.97 | SLC6A2 (0.43) | CRHR1SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL24897458 | 0.94 | CRHR1 (0.43) | CRHR1SLC6A2SLC6A4ALDH1A1MEN1 | |
| Acetic Acid SCHEMBL11348838 | 0.89 | NOTUM (0.46) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL24721182 | 0.86 | AVPR2 (0.45) | ALDH1A1MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL24721271 | 0.86 | AVPR2 (0.45) | ALDH1A1MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL25061884 | 0.86 | AVPR2 (0.45) | ALDH1A1MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL24721145 | 0.86 | AVPR2 (0.45) | ALDH1A1MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL24721105 | 0.86 | AVPR2 (0.45) | ALDH1A1MEN1KMT2ACYP2D6CYP1A2 | |
| SCHEMBL23717802 | 0.85 | SLC6A2 (0.43) | SLC6A2SLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL21902388 | 0.84 | SLC6A2 (0.45) | CRHR1SLC6A2SLC6A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | CRHR1 805/4885SLC6A2 144/4885SLC6A4 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.