Tiliquinol

Tiliquinol

SCHEMBL145245

Cc1ccc(O)c2ncccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 1.00
SLC6A2 P23975 1/20 1.00
KDM4E B2RXH2 8/20 0.61
L3MBTL1 Q9Y468 6/20 0.61
MAPT P10636 5/20 0.61
IDO1 P14902 4/20 0.61
LMNA P02545 3/20 0.61
HSP90AA1 P07900 3/20 0.61
MPI P34949 1/20 0.61
BRD4 O60885 1/20 0.61
METAP2 P50579 1/20 0.61
METAP1 P53582 1/20 0.61
PSMD14 O00487 1/20 0.61
COPS5 Q92905 1/20 0.61
HSP90AB1 P08238 1/20 0.61
PSMB5 P28074 1/20 0.61
COMT P21964 2/20 0.60
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
TDP1 Q9NUW8 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiliquinol SCHEMBL30831638 1.00 HTT (1.00) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL28651750 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL27740177 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL175614 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL2876839 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL4776013 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL27600011 0.98 HTT (0.96) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL2498072 0.90 HTT (0.81) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL28097990 0.87 HTT (0.76) HTTSLC6A2KDM4EL3MBTL1MAPT
Tiliquinol SCHEMBL4465365 0.86 HTT (0.73) HTTSLC6A2KDM4EL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 638 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111875555-B Synthesis method of saccharin-6-acetate 南京合创药业有限公司 2022-07-19 CN claimed
CN-111875555-A Synthesis method of saccharin-6-acetate 南京合创药业有限公司 2020-11-03 CN claimed
EP-2935198-B1 METHOD FOR STABILISING POLYMERISABLE COMPOUNDS BASF SE (DE) 2019-06-05 EP claimed
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS NEOCULI PTY LTD (AU) 2017-10-12 US claimed
CN-106821987-A A kind of liposome and preparation method and application for carrying phenolic hydroxy group insoluble drug 四川大学 2017-06-13 CN claimed
US-9206109-B2 Method of stabilizing polymerizable compounds BASF SE (DE) 2015-12-08 US claimed
EP-2935198-A2 METHOD FOR STABILISING POLYMERISABLE COMPOUNDS BASF SE (DE) 2015-10-28 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20140228571-A1 METHOD OF STABILIZING POLYMERIZABLE COMPOUNDS BASF SE (DE) 2014-08-14 US claimed
WO-2014095437-A2 METHOD FOR STABILISING POLYMERISABLE COMPOUNDS BASF SE (DE) 2014-06-26 WO claimed
US-6362339-B1 ELECTROLUMINESCENCE 3M INNOVATIVE PROPERTIES COMPANY 2002-03-26 US claimed
WO-2000074664-A2 NOVEL IRON CHELATORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING IRON CHELATORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2000-12-14 WO claimed
US-5294519-A Process for preparing printed-circuit board KANSAI PAINT CO., LTD. (JP) 1994-03-15 US claimed
EP-0183567-B1 PROCESS FOR PRODUCING POLYPHENYLENE ETHERS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-03-29 EP claimed
US-4714614-A PSEUDOMONAS AND FERRIC ION CHELATING AGENT COLORADO STATE UNIVERSITY (US) 1987-12-22 US claimed
US-4617372-A MANGANESE SALT, OXINE DERIVATIVES, ALKANOLAMINE AND ALKALINE COMPOUND AS CATALYST MITSUBISHI PETROCHEMICAL CO, LTD. (JP) 1986-10-14 US claimed
EP-0183567-A1 Process for producing polyphenylene ethers MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-06-04 EP claimed
US-4520099-A CONTAINING AN HYDROXYQUINOLINE AS AN ANTIFOGGING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1985-05-28 US claimed
US-4464279-A Magnetic recording medium KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-08-07 US claimed
US-4025609-A CHELATION KAO SOAP CO., LTD. (JA) 1977-05-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170291886-A1 METHODS FOR TREATING PROTOZOAN INFECTIONS DPM1, ABCB11, PIGS HTT 2244/4885SLC6A2 3499/4885KDM4E 3521/4885
US-20140228571-A1 METHOD OF STABILIZING POLYMERIZABLE COMPOUNDS AOC1, AOC2, AOC3 HTT 1480/4885SLC6A2 2940/4885KDM4E 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.