Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005562 | 0.96 | ESR1 (0.42) | ESR1HPGDALDH1A1POLBLMNA | |
| SCHEMBL19204851 | 0.81 | ESR1 (0.42) | ESR1HPGDALDH1A1POLBLMNA | |
| SCHEMBL28348643 | 0.81 | ESR1 (0.42) | ESR1HPGDALDH1A1POLBLMNA | |
| SCHEMBL29005492 | 0.78 | TSHR (0.38) | ALDH1A1POLBLMNAKMT2AGAA | |
| SCHEMBL31190852 | 0.75 | DGAT2 (0.40) | HPGDALDH1A1KDM4EP2RX7IL1B | |
| SCHEMBL29363550 | 0.74 | MAP3K5 (0.37) | ALDH1A1POLBLMNAKMT2AGAA | |
| SCHEMBL1513052 | 0.74 | MAP3K5 (0.37) | ALDH1A1POLBLMNAKMT2AGAA | |
| SCHEMBL25028564 | 0.73 | ESR1 (0.36) | ESR1HPGDALDH1A1 | |
| SCHEMBL31358189 | 0.72 | ESR1 (0.40) | ESR1POLBLMNAMAPTUSP2 | |
| SCHEMBL19204852 | 0.72 | ESR1 (0.35) | ESR1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996926-A | Indole compounds as androgen receptor modulators | 尼多生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |