Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HPD | P32754 | 2/20 | 0.39 |
| ▸ | PARG | Q86W56 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016914 | 0.87 | MMP13 (0.41) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL14916111 | 0.87 | PKM (0.44) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| Hydrochloric Acid SCHEMBL14916909 | 0.87 | PKM (0.44) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL322594 | 0.86 | MMP13 (0.46) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL322222 | 0.85 | HDAC1 (0.41) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL15094059 | 0.84 | KDM4E (0.40) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL14916199 | 0.84 | MMP13 (0.47) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL15016935 | 0.84 | MMP13 (0.41) | MMP13SLC22A8HDAC1HDAC11HDAC8 | |
| SCHEMBL15093749 | 0.82 | HDAC1 (0.42) | HDAC1HDAC11HDAC8HDAC6HPD | |
| SCHEMBL15093892 | 0.82 | HDAC1 (0.39) | MMP13SLC22A8HDAC1HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170231998-A1 | Pyrazolopyridine Derivatives, Preparation Process Therefor And Therapeutic Use Thereof | SANOFI (FR) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231998-A1 | Pyrazolopyridine Derivatives, Preparation Process Therefor And Therapeutic Use Thereof | FGF1, FGF2, FGFR1 | MMP13 1510/4885SLC22A8 1571/4885HDAC1 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.