Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921722 | 0.95 | UTS2R (0.38) | MEN1KMT2ACRHBPCRHR2UTS2R | |
| SCHEMBL1920293 | 0.89 | KCNA5 (0.37) | CNR1MEN1KMT2APOLBCRHBP | |
| SCHEMBL1630647 | 0.88 | CNR1 (0.43) | CNR1MEN1KMT2APOLBCRHBP | |
| SCHEMBL1920837 | 0.88 | CRHBP (0.35) | CNR1POLBCRHBPCRHR2UTS2R | |
| SCHEMBL1921777 | 0.85 | UTS2R (0.37) | MEN1KMT2ACRHBPCRHR2UTS2R | |
| SCHEMBL3424582 | 0.84 | CRHBP (0.41) | CNR1MEN1KMT2APOLBCRHBP | |
| SCHEMBL1630544 | 0.83 | HSD11B1 (0.47) | MEN1KMT2APOLBCRHBPCRHR2 | |
| SCHEMBL1920221 | 0.83 | CRHBP (0.40) | MEN1KMT2APOLBCRHBPCRHR2 | |
| SCHEMBL1921724 | 0.82 | UTS2R (0.38) | POLBCRHBPCRHR2UTS2RHSD11B1 | |
| SCHEMBL1631802 | 0.82 | KCNA5 (0.43) | CNR1MEN1KMT2APOLBCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245006-B1 | SULFONAMIDES AS OREXIN ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2011-06-01 | — | — | EP | disclosed |