SCHEMBL19207400

SCHEMBL19207400

O=c1[nH]c2cc(Br)c(=O)[nH]c2cc1Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 13/20 0.56
GRIN3B O60391 13/20 0.56
GRIN1 Q05586 13/20 0.56
GRIN2A Q12879 13/20 0.56
GRIN2B Q13224 13/20 0.56
GRIN2C Q14957 13/20 0.56
GRIN3A Q8TCU5 13/20 0.56
GRIA1 P42261 3/20 0.48
GRIA2 P42262 3/20 0.48
GRIA3 P42263 3/20 0.48
GRIA4 P48058 3/20 0.48
KDM4E B2RXH2 3/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
TSHR P16473 2/20 0.48
BLM P54132 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4704929 0.88 GRIN2D (0.61) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL463673 0.78 GRIN2D (0.52) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4704585 0.78 CASP7 (0.58) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1238471 0.74 DAO (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30355132 0.74 DAO (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30355127 0.74 DAO (0.60) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30807513 0.74 GRIN2D (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30807512 0.74 GRIN2D (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL18548573 0.73 CYP19A1 (0.49) LMNAHPGD
SCHEMBL16627567 0.73 METAP2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11603431-B2 Organic semiconductors Raynergy Tek Incorporation (TW) 2023-03-14 US disclosed
EP-3411374-B9 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2023-01-11 EP disclosed
EP-3411374-B9 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2023-01-11 EP disclosed
EP-3411374-B1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS RAYNERGY TEK INC (TW) 2022-08-10 EP disclosed
US-20190040188-A1 ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
US-20190040188-A1 ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
EP-3411374-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS Merck Patent GmbH (DE) 2018-12-12 EP disclosed
WO-2017133752-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed
WO-2017133752-A1 [1,5]NAPHTHYRIDINE COMPOUNDS AND POLYMERS AS SEMICONDUCTORS MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed
US-20150307465-A1 Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use MERCK SHARP & DOHME CORP. (US) 2015-10-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040188-A1 ORGANIC SEMICONDUCTORS OCIAD2, OCIAD1, PPOX GRIN2D 136/4885GRIN3B 2224/4885GRIN1 1688/4885
US-11603431-B2 Organic semiconductors OCIAD2, OCIAD1, PPOX GRIN2D 136/4885GRIN3B 2224/4885GRIN1 1688/4885
US-20150307465-A1 Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use BACE1, BACE2, APP GRIN2D 2349/4885GRIN3B 3669/4885GRIN1 2510/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.