Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 9/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.64 |
| ▸ | USP2 | O75604 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19254305 | 0.91 | CSNK2A1 (0.70) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19254575 | 0.85 | CSNK2A1 (0.67) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19207487 | 0.82 | MAPT (0.72) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19207411 | 0.82 | CSNK2A1 (0.65) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19254727 | 0.81 | CSNK2A1 (0.65) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19207420 | 0.80 | CSNK2A1 (0.61) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19254805 | 0.80 | CSNK2A1 (0.85) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL28015906 | 0.80 | CSNK2A1 (0.89) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL19254304 | 0.79 | CSNK2A1 (0.59) | CSNK2A1HSD17B10KDM4ENPSR1USP2 | |
| SCHEMBL22400134 | 0.79 | CSNK2A1 (0.59) | CSNK2A1HSD17B10KDM4ENPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10765681-B2 | Purine compounds possessing anticancer activity | ACADEMIA SINICA (TW) | 2020-09-08 | — | — | US | disclosed |
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2018-12-27 | — | — | US | disclosed |
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180369249-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | NTPCR, PNP, NUDT1 | CSNK2A1 2675/4885HSD17B10 2898/4885KDM4E 3979/4885 |
| US-10765681-B2 | Purine compounds possessing anticancer activity | NTPCR, PNP, NUDT1 | CSNK2A1 2675/4885HSD17B10 2898/4885KDM4E 3979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.