Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 13/20 | 0.41 |
| ▸ | ADH1C | P00326 | 10/20 | 0.41 |
| ▸ | ADH1B | P00325 | 5/20 | 0.41 |
| ▸ | ADH4 | P08319 | 3/20 | 0.41 |
| ▸ | ADH7 | P40394 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11734533 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| SCHEMBL11341547 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| Cyclopentanecarbaldehyde SCHEMBL14575123 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| SCHEMBL493755 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| SCHEMBL3036861 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| Cycloheptane Carbaldehyde SCHEMBL95620 | 1.00 | — | — | |
| SCHEMBL59918 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| SCHEMBL329469 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| Cycloundecane Carbaldehyde SCHEMBL1901240 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 | |
| SCHEMBL3027683 | 1.00 | ADH1A (0.41) | ADH1AADH1CADH1BADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2014-06-12 | — | — | US | claimed |
| US-8680234-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS OY (FI) | 2014-03-25 | — | — | US | claimed |
| US-8329645-B2 | Polymyxin derivatives and uses thereof | NORTHERN ANTIBIOTICS LTD. (FI) | 2012-12-11 | — | — | US | claimed |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS OY (FI) | 2010-11-18 | — | — | US | claimed |
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | NORTHERN ANTIBIOTICS LTD. (FI) | 2009-08-27 | — | — | US | claimed |
| CN-118852163-A | Macrocyclic compound containing heteroatoms, and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-109790284-B | Polyphenol compound and process for producing the same | 三菱化学株式会社 | 2021-09-21 | — | — | CN | disclosed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-10851039-B2 | Polyhydric phenol compound and method of producing same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2020-12-01 | — | — | US | disclosed |
| US-10793499-B2 | — | — | 2020-10-06 | — | — | US | disclosed |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2020-06-18 | — | — | US | disclosed |
| US-10478385-B2 | Dental adhesive material kit | KURARAY NORITAKE DENTAL INC. (JP) | 2019-11-19 | — | — | US | disclosed |
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0914307-A1 | ENZYMATICALLY REMOVABLE LINKERS FOR SOLID PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998001406-A1 | ENZYMATICALLY REMOVABLE LINKERS FOR SOLID PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| US-5658926-A | ANTICOAGULANTS, ANTIHISTAMINES, ANTIARRHYTHMIC, CARTIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5506239-A | Carbostyril derivative and platelets aggregation inhibitory agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0569592-A1 | CARBOSTYRIL DERIVATIVE AND PLATELET AGGLUTINATION INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215677-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ADH1A 4879/4885ADH1C 4883/4885ADH1B 4781/4885 |
| US-10478385-B2 | Dental adhesive material kit | VCL, MVD, MAT2B | ADH1A 865/4885ADH1C 1060/4885ADH1B 903/4885 |
| US-10851039-B2 | Polyhydric phenol compound and method of producing same | RB1, FHIT, H1-4 | ADH1A 646/4885ADH1C 467/4885ADH1B 123/4885 |
| US-20140162937-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | SLC11A2, TLR2, TLR5 | ADH1A 4872/4885ADH1C 4883/4885ADH1B 4804/4885 |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | DDOST, MGAM, MSN | ADH1A 4620/4885ADH1C 4618/4885ADH1B 4746/4885 |
| US-20100292136-A1 | POLYMYXIN DERIVATIVES AND USES THEREOF | C5, C9, C3AR1 | ADH1A 4879/4885ADH1C 4883/4885ADH1B 4781/4885 |
| US-10793499-B2 | — | RB1, H1-4, TPD52L2 | ADH1A 817/4885ADH1C 772/4885ADH1B 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.