SCHEMBL19208367

SCHEMBL19208367

C[C@@H](N)CCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.31
OPRM1 P35372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937359 1.00 DUT (0.31) DUTOPRM1
SCHEMBL27873328 1.00 DUT (0.31) DUTOPRM1
SCHEMBL24387135 0.84 OPRM1 (0.39) DUTOPRM1
SCHEMBL15307671 0.82 ALDH1A1 (0.34) DUT
SCHEMBL19364204 0.80
SCHEMBL1368230 0.79
SCHEMBL1369535 0.79
SCHEMBL1366967 0.79
SCHEMBL1313907 0.78 MAPK1 (0.33) DUT
SCHEMBL25461568 0.78 DUT (0.31) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3411411-A1 BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF Biocryst Pharmaceuticals, Inc. (US) 2018-12-12 EP disclosed
WO-2017136395-A1 BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF BIOCRYST PHARMACEUTICALS, INC. (US) 2017-08-10 WO disclosed