Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536947 | 0.85 | TAAR1 (0.41) | DUTKCNH2IDO1SLC2A1 | |
| SCHEMBL1244821 | 0.80 | DUT (0.36) | DUT | |
| SCHEMBL1244866 | 0.80 | TAAR1 (0.42) | DUTIDO1MPO | |
| SCHEMBL30922515 | 0.75 | DUT (0.36) | DUTKCNH2DGAT1SLC2A1 | |
| SCHEMBL23908432 | 0.74 | DUT (0.37) | DUT | |
| SCHEMBL30667522 | 0.74 | TAAR1 (0.41) | DUTIDO1 | |
| SCHEMBL12634902 | 0.74 | TAAR1 (0.41) | DUTIDO1 | |
| SCHEMBL15054017 | 0.74 | MPO (0.41) | DUTAKR1B1IDO1MPO | |
| SCHEMBL9566221 | 0.74 | TAAR1 (0.41) | DUTIDO1 | |
| SCHEMBL8069572 | 0.74 | DUT (0.39) | DUTIDO1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411411-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | Biocryst Pharmaceuticals, Inc. (US) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017136395-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | BIOCRYST PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |