Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | DUT | P33316 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438941 | 0.86 | CHRM2 (0.44) | TAAR1IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19208399 | 0.85 | DUT (0.36) | IDO1DUTKCNH2SLC2A1 | |
| SCHEMBL1244866 | 0.81 | TAAR1 (0.42) | TAAR1IDO1SLC6A4AOC3DUT | |
| SCHEMBL8069572 | 0.81 | DUT (0.39) | IDO1DUTSLC2A1 | |
| SCHEMBL12634902 | 0.81 | TAAR1 (0.41) | TAAR1IDO1DUT | |
| SCHEMBL15054017 | 0.81 | MPO (0.41) | TAAR1IDO1SLC6A4DUT | |
| SCHEMBL9566221 | 0.81 | TAAR1 (0.41) | TAAR1IDO1DUT | |
| SCHEMBL30667522 | 0.81 | TAAR1 (0.41) | TAAR1IDO1DUT | |
| SCHEMBL30416922 | 0.80 | TAAR1 (0.47) | TAAR1IDO1AOC3KCNH2 | |
| SCHEMBL30416478 | 0.80 | TAAR1 (0.47) | TAAR1IDO1AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |