Sugi Predict

Sugi Predict / Compounds / SCHEMBL192086

SCHEMBL192086

SCHEMBL192086

CCOP(=O)(CS(=O)(=O)OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 2/20 0.48
▸ PPARD Q03181 2/20 0.41
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ TP53 P04637 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15966600 0.90 TSHR (0.43) TSHRPPARDCA1CA2TP53
SCHEMBL11543347 0.84 TSHR (0.41) TSHRPPARDTP53TDP1
SCHEMBL4248142 0.82 TSHR (0.40) TSHRPPARDTP53TDP1
SCHEMBL16076962 0.82 CA1 (0.31) TSHRCA1CA2
SCHEMBL2313241 0.82 TSHR (0.48) TSHRPPARDTP53TDP1MEN1
SCHEMBL15912196 0.82 CA1 (0.37) TSHRCA1CA2
SCHEMBL159202 0.81 TSHR (0.52) TSHRPPARDCA1CA2TP53
SCHEMBL14052761 0.81 TSHR (0.43) TSHRPPARDTP53TDP1
SCHEMBL15800939 0.81 TSHR (0.39) TSHRPPARDTP53TDP1
Lithium Ion SCHEMBL8714807 0.77 TSHR (0.48) TSHRPPARDCA1CA2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541830-A1 PROCESS FOR PRODUCING POLYURETHANE FOAM Covestro Deutschland AG (DE) 2025-04-23 — — EP claimed
CN-107382951-B Genipin derivatives, and preparation and application thereof 上海交通大学 2020-09-18 — — CN claimed
EP-4541830-A1 PROCESS FOR PRODUCING POLYURETHANE FOAM Covestro Deutschland AG (DE) 2025-04-23 — — EP disclosed
US-20210070798-A1 Inhibitors of E1 activating enzymes TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-03-11 — — US disclosed
US-20190255052-A1 Inhibitors of E1 Activating Enzymes MILLENNIUM PHARMACEUTICALS, INC. (US) 2019-08-22 — — US disclosed
US-20180086785-A1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES MILLENNIUM PHARMACEUTICALS, INC. 2018-03-29 — — US disclosed
US-20180086785-A1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES MILLENNIUM PHARMACEUTICALS, INC. 2018-03-29 — — US disclosed
US-20170136024-A1 INHIBITORS OF E1 ACTIVATING ENZYMES MILLENNIUM PHARMACEUTICALS, INC. 2017-05-18 — — US disclosed
US-20170073367-A9 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES MILLENIUM PHARMACEUTICALS, INC. 2017-03-16 — — US disclosed
US-20170073367-A9 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES MILLENIUM PHARMACEUTICALS, INC. 2017-03-16 — — US disclosed
US-20170073367-A9 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES MILLENIUM PHARMACEUTICALS, INC. 2017-03-16 — — US disclosed
US-20090163586-A1 Bis-(Sulfonylamino) Derivatives in Therapy 205 ASTRAZENECA AB (SE) 2009-06-25 — — US disclosed
EP-1989206-A2 INHIBITORS OF E1 ACTIVATING ENZYME MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-11-12 — — EP disclosed
US-20080051404-A1 Heteroaryl compounds useful as inhibitors of E1 activating enzymes MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-02-28 — — US disclosed
EP-1848718-A1 INHIBITORS OF E1 ACTIVATING ENZYMES MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-31 — — EP disclosed
US-20070191293-A1 Inhibitors of E1 activating enzymes MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-08-16 — — US disclosed
WO-2007092213-A2 INHIBITORS OF E1 ACTIVATING ENZYME MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-08-16 — — WO disclosed
US-20070135469-A1 Vinylsulfonate and vinylsulfonamide compounds NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2007-06-14 — — US disclosed
US-20060189636-A1 Inhibitors of E1 activating enzymes MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-08-24 — — US disclosed
WO-2006084281-A1 INHIBITORS OF E1 ACTIVATING ENZYMES MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-08-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086785-A1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES TYMP, TYMS, PPA1 TSHR 4073/4885PPARD 941/4885CA1 3790/4885
US-20170073367-A9 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES TYMP, TYMS, PPA1 TSHR 4073/4885PPARD 941/4885CA1 3790/4885
US-20170136024-A1 INHIBITORS OF E1 ACTIVATING ENZYMES ECE1, RNASE1, RCE1 TSHR 4091/4885PPARD 2445/4885CA1 2434/4885
US-20090163586-A1 Bis-(Sulfonylamino) Derivatives in Therapy 205 PTGER1, SULT2A1, SULT1E1 TSHR 974/4885PPARD 659/4885CA1 3346/4885
US-20080051404-A1 Heteroaryl compounds useful as inhibitors of E1 activating enzymes RCE1, ECE1, UBE2E1 TSHR 4251/4885PPARD 2334/4885CA1 3932/4885
US-20210070798-A1 Inhibitors of E1 activating enzymes ECE1, RNASE1, RCE1 TSHR 4091/4885PPARD 2445/4885CA1 2434/4885
US-20190255052-A1 Inhibitors of E1 Activating Enzymes ECE1, RNASE1, RCE1 TSHR 4091/4885PPARD 2445/4885CA1 2434/4885
US-20070135469-A1 Vinylsulfonate and vinylsulfonamide compounds PPARA, PPARG, PPARD TSHR 172/4885PPARD 3/4885CA1 4672/4885
US-20060189636-A1 Inhibitors of E1 activating enzymes ECE1, RNASE1, RCE1 TSHR 4091/4885PPARD 2445/4885CA1 2434/4885
US-20070191293-A1 Inhibitors of E1 activating enzymes ECE1, RNASE1, RCE1 TSHR 4091/4885PPARD 2445/4885CA1 2434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.