Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1921517 | 0.93 | ITGB3 (0.60) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Tyrosine SCHEMBL3121863 | 0.89 | SLC7A5 (0.56) | ITGB3ITGA2BTHRBGSRSLC7A5 | |
| SCHEMBL571283 | 0.88 | ITGB3 (0.65) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Lysine SCHEMBL1921682 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Tyrosine SCHEMBL1921852 | 0.88 | SLC7A5 (0.55) | ITGB3ITGA2BTHRBGSRSLC7A5 | |
| Leucine SCHEMBL4586599 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Lysine SCHEMBL4198912 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BTHRBPTPN1GSR | |
| SCHEMBL4629444 | 0.84 | SLC7A5 (0.56) | ITGB3ITGA2BTHRBPTPN1SLC7A5 | |
| SCHEMBL9937712 | 0.84 | SLC7A5 (0.56) | ITGB3ITGA2BTHRBPTPN1SLC7A5 | |
| Lysine SCHEMBL5358311 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BTHRBPTPN1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4800481-B2 | — | — | 2011-10-26 | — | — | JP | claimed |
| US-20100298227-A1 | Treatment of autoimmune conditions with Copolymer 1 and related copolymers | President and Fellows of Harvard College and Yeda Research | 2010-11-25 | — | — | US | claimed |
| US-20080207526-A1 | Synthetic peptides and methods of use for autoimmune disease therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2008-08-28 | — | — | US | claimed |
| EP-1098902-A4 | TREATMENT OF AUTOIMMUNE CONDITIONS WITH COPOLYMER 1 AND RELATED COPOLYMERS AND PEPTIDES | YEDA RES & DEV (IL) | 2002-07-24 | — | — | EP | claimed |
| EP-1105414-A2 | SYNTHETIC PEPTIDES AND METHODS OF USE FOR AUTOIMMUNE DISEASE THERAPIES | President And Fellows of Harvard College (US) | 2001-06-13 | — | — | EP | claimed |
| EP-1098902-A1 | TREATMENT OF AUTOIMMUNE CONDITIONS WITH COPOLYMER 1 AND RELATED COPOLYMERS AND PEPTIDES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2001-05-16 | — | — | EP | claimed |
| WO-2000005250-A9 | TREATMENT OF AUTOIMMUNE CONDITIONS WITH COPOLYMER 1 AND RELATED COPOLYMERS AND PEPTIDES | YEDA RES & DEV (IL) | 2000-10-12 | — | — | WO | claimed |
| WO-2000005250-A1 | TREATMENT OF AUTOIMMUNE CONDITIONS WITH COPOLYMER 1 AND RELATED COPOLYMERS AND PEPTIDES | YEDA RESEARCH AND DEVELOPMENT CO., LTD (IL) | 2000-02-03 | — | — | WO | claimed |
| WO-2000005249-A2 | SYNTHETIC PEPTIDES AND METHODS OF USE FOR AUTOIMMUNE DISEASE THERAPIES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-03 | — | — | WO | claimed |
| US-9066905-B2 | Synthetic peptides and methods of use for autoimmune disease therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-30 | — | — | US | disclosed |
| EP-2848627-A2 | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2015-03-18 | — | — | EP | disclosed |
| EP-2327712-A2 | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2011-06-01 | — | — | EP | disclosed |
| US-7566767-B2 | Synthetic peptides and methods of use for autoimmune disease therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080207526-A1 | Synthetic peptides and methods of use for autoimmune disease therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2008-08-28 | — | — | US | disclosed |
| US-20040006022-A1 | Synthetic peptides and methods of use for autoimmune disease therapies | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-01-08 | — | — | US | disclosed |
| EP-1105414-A2 | SYNTHETIC PEPTIDES AND METHODS OF USE FOR AUTOIMMUNE DISEASE THERAPIES | President And Fellows of Harvard College (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000005249-A2 | SYNTHETIC PEPTIDES AND METHODS OF USE FOR AUTOIMMUNE DISEASE THERAPIES | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2000-02-03 | — | — | WO | disclosed |