Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571283 | 0.92 | ITGB3 (0.65) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Lysine SCHEMBL1921517 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Tyrosine SCHEMBL3485476 | 0.87 | ITGB3 (0.60) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Phenylalanine SCHEMBL1921138 | 0.87 | ITGB3 (0.44) | ITGB3ITGA2BTHRBSLC7A5ALPI | |
| SCHEMBL829349 | 0.87 | SLC7A5 (0.51) | ITGB3ITGA2BPTPN1SLC7A5ALPI | |
| Cysteine SCHEMBL9755060 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BTHRBPTPN1GSR | |
| Lysine SCHEMBL4198912 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BTHRBPTPN1GSR | |
| SCHEMBL1920941 | 0.85 | ITGB3 (0.55) | ITGB3ITGA2BTHRBPTPN1GSR | |
| SCHEMBL10613823 | 0.85 | NPY4R (0.47) | ITGB3ITGA2BTHRBSLC7A5MMP2 | |
| Glutamic Acid SCHEMBL1696963 | 0.85 | ITGB3 (0.57) | ITGB3ITGA2BTHRBPTPN1GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850497-A | YKL-40 monoclonal antibody and preparation method and application thereof | 陕西脉元生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-1487395-B1 | METHODS OF DIAGNOSING LIVER FIBROSIS | NESTEC SA (CH) | 2013-04-10 | — | — | EP | disclosed |
| EP-1487395-A4 | METHODS OF DIAGNOSING LIVER FIBROSIS | PROMETHEUS LAB INC (US) | 2008-09-10 | — | — | EP | disclosed |
| US-20060084057-A1 | Methods of diagnosing liver fibrosis | PROMETHEUS LABORATORIES | 2006-04-20 | — | — | US | disclosed |
| US-6986995-B2 | Methods of diagnosing liver fibrosis | PROMETHEUS LABORATORIES, INC. (US) | 2006-01-17 | — | — | US | disclosed |
| EP-1487395-A2 | METHODS OF DIAGNOSING LIVER FIBROSIS | Prometheus Laboratories, Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20030175686-A1 | Methods of diagnosing liver fibrosis | PROMETHEUS LABORATORIES, INC. | 2003-09-18 | — | — | US | disclosed |
| WO-2003073822-A2 | METHODS OF DIAGNOSING LIVER FIBROSIS | PROMETHEUS LABORATORIES, INC. (US) | 2003-09-12 | — | — | WO | disclosed |