Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.65 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 1/20 | 0.43 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL3485476 | 0.95 | ITGB3 (0.60) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Cysteine SCHEMBL9755060 | 0.94 | ITGB3 (0.58) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Glutamic Acid SCHEMBL1696963 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Leucine SCHEMBL4586599 | 0.92 | ITGB3 (0.56) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Lysine SCHEMBL1921517 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Lysine SCHEMBL4198912 | 0.89 | ITGB3 (0.53) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| SCHEMBL1920941 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Lysine SCHEMBL4610451 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Lysine SCHEMBL5358311 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BGSRPTPN1SLC7A5 | |
| Lysine SCHEMBL3497594 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BGSRPTPN1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298227-A1 | Treatment of autoimmune conditions with Copolymer 1 and related copolymers | President and Fellows of Harvard College and Yeda Research | 2010-11-25 | — | — | US | claimed |
| WO-2002086153-A1 | DETERMINING RESISTANCE TO A $G(b)-LACTAM-CONTAINING ANTIBIOTIC BY COMPARING THE RATIO OF TWO $G(b)-LACTAMASE GENES | DIATECH PTY LTD (AU) | 2002-10-31 | — | — | WO | claimed |
| US-20230405143-A1 | TYROSINE-BASED ANTIBODY CONJUGATES | SYNAFFIX B.V. (NL) | 2023-12-21 | — | — | US | disclosed |
| CN-117243894-A | Antidote liposome for central nervous toxicant poisoning | 中国人民解放军新疆军区总医院 | 2023-12-19 | — | — | CN | disclosed |
| EP-4247432-A1 | TYROSINE-BASED ANTIBODY CONJUGATES | Synaffix B.V. (NL) | 2023-09-27 | — | — | EP | disclosed |
| CN-116744977-A | Tyrosine-based antibody conjugates | 西纳福克斯股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-04-20 | — | — | US | disclosed |
| EP-4074694-A1 | AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF | Massachusetts Institute Of Technology (US) | 2022-10-19 | — | — | EP | disclosed |
| WO-2022108452-A1 | TYROSINE-BASED ANTIBODY CONJUGATES | SYNAFFIX B.V. (NL) | 2022-05-27 | — | — | WO | disclosed |
| US-10918741-B2 | PSMA-targeting imaging agents | THE CLEVELAND CLINIC FOUNDATION (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-22 | — | — | US | disclosed |
| WO-2003034068-A1 | LOCALIZATION OF DISORDERS ASSOCIATED WITH KALLIKREINS | MOUNT SINAI HOSPITAL (CA) | 2003-04-24 | — | — | WO | disclosed |
| WO-2002097438-A1 | METHOD OF DETECTING AND MONITORING PROSTATE AND OVARIAN CANCERS | MOUNT SINAI HOSPITAL (CA) | 2002-12-05 | — | — | WO | disclosed |
| WO-2002086153-A1 | DETERMINING RESISTANCE TO A $G(b)-LACTAM-CONTAINING ANTIBIOTIC BY COMPARING THE RATIO OF TWO $G(b)-LACTAMASE GENES | DIATECH PTY LTD (AU) | 2002-10-31 | — | — | WO | disclosed |
| WO-2002037112-A2 | DETECTION OF OVARIAN CANCER | MOUNT SINAI HOSPITAL (CA) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002035232-A2 | METHOD FOR DETECTING OVARIAN CANCER BASED ON HUMAN KALLIKREIN 6 (HK6) | MOUNT SINAI HOSPITAL (CA) | 2002-05-02 | — | — | WO | disclosed |
| US-H1312-H | Method for the preparation of gyk-dtpa | CYTOGEN CORPORATION (US) | 1994-05-03 | — | — | US | disclosed |
| WO-1991005605-A1 | CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS | KOSAK KENNETH M (US) | 1991-05-02 | — | — | WO | disclosed |
| US-4826817-A | DRUG DELIVERY | BROWN THOMAS E (US) | 1989-05-02 | — | — | US | disclosed |
| US-4153687-A | Derivatives, having an inhibitory action against protease and an antiphlogistic action, of the trypsin-kallikrein inhibitor obtained from cattle organs (BPTI), their preparation and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | ITGB3 2476/4885ITGA2B 2798/4885GSR 1896/4885 |
| US-10918741-B2 | PSMA-targeting imaging agents | FOLH1, PSMA1, PSMA2 | ITGB3 691/4885ITGA2B 1141/4885GSR 4335/4885 |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | ITGB3 2476/4885ITGA2B 2798/4885GSR 1896/4885 |
| US-20230405143-A1 | TYROSINE-BASED ANTIBODY CONJUGATES | TYR, TH, TYRO3 | ITGB3 569/4885ITGA2B 568/4885GSR 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.