Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209478 | 0.89 | XDH (0.48) | XDHKDM4EPOLBNPSR1RXFP1 | |
| SCHEMBL19209500 | 0.88 | XDH (0.46) | XDHKDM4EHSD17B10ALDH1A1MAPT | |
| SCHEMBL1889329 | 0.88 | CYP11B2 (0.49) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL1818457 | 0.87 | CYP4F2 (0.46) | KDM4EHSD17B10ALDH1A1HPGDCYP11B1 | |
| SCHEMBL1815801 | 0.86 | CYP11B2 (0.43) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL1818710 | 0.84 | CYP11B2 (0.42) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL19257720 | 0.84 | XDH (0.42) | XDHKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL19209422 | 0.84 | XDH (0.48) | XDHKDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL1812968 | 0.84 | CYP11B2 (0.41) | KDM4EHSD17B10ALDH1A1HPGDMAPK1 | |
| SCHEMBL19209475 | 0.83 | XDH (0.41) | XDHKDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |