Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209475 | 0.91 | XDH (0.41) | XDHS1PR1NPC1RAB9AHSD17B10 | |
| SCHEMBL19209443 | 0.89 | S1PR1 (0.51) | XDHS1PR1HSD17B10 | |
| SCHEMBL38659061 | 0.89 | MTNR1A (0.42) | HSD17B10KDM4EALDH1A1MTNR1AMTNR1B | |
| SCHEMBL1890644 | 0.89 | MTNR1A (0.42) | HSD17B10KDM4EALDH1A1MTNR1AMTNR1B | |
| SCHEMBL19257570 | 0.87 | XDH (0.43) | XDHS1PR1NPC1RAB9AHSD17B10 | |
| SCHEMBL19209500 | 0.86 | XDH (0.46) | XDHNPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL19209436 | 0.84 | XDH (0.46) | XDHNPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL19209422 | 0.83 | XDH (0.48) | XDHNPC1RAB9AHSD17B10KDM4E | |
| SCHEMBL15399809 | 0.81 | MTNR1A (0.39) | HSD17B10KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL19209427 | 0.81 | PPARG (0.44) | KDM4EALDH1A1USP2MAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |