Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19209453 | 0.94 | FFAR1 (0.45) | FFAR1FFAR4PTGER4PTGER3POLB | |
| SCHEMBL19209427 | 0.89 | PPARG (0.44) | MTNR1AMTNR1BMAPK14 | |
| SCHEMBL1889009 | 0.86 | FFAR1 (0.54) | FFAR1FFAR4PTGER4PTGER3MTNR1A | |
| SCHEMBL12660792 | 0.84 | POLB (0.52) | FFAR1FFAR4PTGER4PTGER3MTNR1A | |
| SCHEMBL19257206 | 0.83 | FFAR1 (0.53) | FFAR1FFAR4PTGER4PTGER3MTNR1A | |
| SCHEMBL19209418 | 0.83 | PPARG (0.44) | MTNR1AMTNR1BMAPK14 | |
| SCHEMBL1809637 | 0.82 | SLC1A3 (0.45) | FFAR1FFAR4MTNR1AMTNR1BPOLB | |
| SCHEMBL19209414 | 0.82 | FFAR1 (0.50) | FFAR1FFAR4PTGER4PTGER3MTNR1A | |
| SCHEMBL1891972 | 0.82 | POLB (0.50) | FFAR1FFAR4MTNR1AMTNR1BPOLB | |
| SCHEMBL38659657 | 0.82 | POLB (0.50) | FFAR1FFAR4MTNR1AMTNR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017134146-A1 | GPBP INHIBITORS AND USES AND SCALEABLE SYNTHESIS THEREOF | FIBROSTATIN, S.L. (ES) | 2017-08-10 | — | — | WO | disclosed |