SCHEMBL38659657

SCHEMBL38659657

COc1ccc(-c2ccc(-c3ccc(OC)c(C)c3)c(C)c2)c(CCC(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
HSD17B10 Q99714 1/20 0.49
FFAR1 O14842 9/20 0.46
FFAR4 Q5NUL3 2/20 0.43
HTT P42858 1/20 0.43
S1PR1 P21453 1/20 0.42
MAPT P10636 1/20 0.42
MTNR1A P48039 1/20 0.42
MTNR1B P49286 1/20 0.42
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891972 1.00 POLB (0.50) POLBHSD17B10FFAR1FFAR4HTT
SCHEMBL19257272 0.93 POLB (0.50) POLBHSD17B10FFAR1HTTS1PR1
SCHEMBL15602007 0.91 POLB (0.46) POLBHSD17B10FFAR1FFAR4HTT
SCHEMBL15602073 0.91 RAB9A (0.44) POLBHSD17B10FFAR1MAPTMTNR1A
SCHEMBL19257588 0.91 HSD17B10 (0.43) POLBHSD17B10FFAR1MAPTMTNR1A
SCHEMBL12660792 0.90 POLB (0.52) POLBHSD17B10FFAR1FFAR4HTT
SCHEMBL19209443 0.88 S1PR1 (0.51) POLBHSD17B10S1PR1
SCHEMBL38659061 0.87 MTNR1A (0.42) HSD17B10FFAR1MTNR1AMTNR1B
SCHEMBL1890644 0.87 MTNR1A (0.42) HSD17B10FFAR1MTNR1AMTNR1B
SCHEMBL19257560 0.86 POLB (0.46) POLBHSD17B10FFAR1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099533-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS UNIVERSITAT DE VALÈNCIA (ES) 2026-05-15 WO claimed
WO-2026099533-A1 TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS UNIVERSITAT DE VALÈNCIA (ES) 2026-05-15 WO disclosed