Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419549 | 0.88 | KMT2A (0.40) | CTSKALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL15009171 | 0.82 | NR1H2 (0.42) | CTSKALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7441833 | 0.81 | ACACB (0.40) | GPR119CTSKALDH1A1KMT2AMEN1 | |
| SCHEMBL25819260 | 0.81 | ALDH1A1 (0.52) | GPR119CTSKALDH1A1KMT2AMEN1 | |
| SCHEMBL3625257 | 0.81 | ACACB (0.40) | CTSKALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL5914370 | 0.79 | KMT2A (0.39) | GPR119CTSKALDH1A1KMT2AMEN1 | |
| SCHEMBL30965680 | 0.78 | EPHX1 (0.40) | CTSKALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7655298 | 0.78 | GPR119 (0.51) | GPR119STSTGFBR1KDM4EPKM | |
| SCHEMBL15654440 | 0.77 | CHRM2 (0.41) | CTSKALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL27349219 | 0.77 | CTSK (0.41) | CTSKALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134685-A2 | NOVEL HYDRAZINO COMPOUNDS AS BTK INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |