Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125526 | 1.00 | MYC (0.40) | MYCTSHRSMN1; SMN2TTRCA12 | |
| SCHEMBL28958546 | 0.98 | MYC (0.39) | MYCTSHRSMN1; SMN2TTRCA12 | |
| SCHEMBL28958588 | 0.83 | CA12 (0.47) | MYCTSHRSMN1; SMN2TTRCA12 | |
| SCHEMBL28161246 | 0.82 | CA12 (0.52) | MYCTSHRSMN1; SMN2TTRCA12 | |
| SCHEMBL998537 | 0.80 | MYC (0.41) | MYCTSHRSMN1; SMN2TTRCA12 | |
| SCHEMBL31194881 | 0.78 | ALDH1A1 (0.58) | MYCTSHRALDH1A1HTTPOLB | |
| SCHEMBL29890659 | 0.78 | PTGS2 (0.41) | CA12CA2CA9ALDH1A1HTT | |
| SCHEMBL3877411 | 0.78 | ALDH1A1 (0.58) | MYCTSHRALDH1A1HTTPOLB | |
| SCHEMBL2468180 | 0.78 | CA2 (0.58) | CA12CA2CA9CDK2 | |
| SCHEMBL18297463 | 0.78 | PTGS2 (0.41) | CA12CA2CA9ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115589736-A | Perovskite composite layer and solar cell | 嘉庚创新实验室 | 2023-01-10 | — | — | CN | disclosed |
| US-8283476-B2 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI (FR) | 2012-10-09 | — | — | US | disclosed |
| US-8283476-B2 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI (FR) | 2012-10-09 | — | — | US | disclosed |
| EP-2134682-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | SANOFI SA (FR) | 2011-12-14 | — | — | EP | disclosed |
| US-8026375-B2 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2011-09-27 | — | — | US | disclosed |
| US-8026375-B2 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2011-09-27 | — | — | US | disclosed |
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | disclosed |
| EP-2170833-B1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI AVENTIS (FR) | 2011-06-01 | — | — | EP | disclosed |
| US-20100234601-A1 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI-AVENTIS (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20100234601-A1 | Transition metal catalyzed synthesis of 2H-indazoles | SANOFI-AVENTIS (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20100168429-A1 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2010-07-01 | — | — | US | disclosed |
| US-20100168429-A1 | Transition metal catalyzed synthesis of N-aminoindoles | SANOFI-AVENTIS (FR) | 2010-07-01 | — | — | US | disclosed |
| EP-2170833-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | disclosed |
| EP-2170833-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | Sanofi-Aventis (FR) | 2010-04-07 | — | — | EP | disclosed |
| EP-2134682-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | Sanofi-Aventis (FR) | 2009-12-23 | — | — | EP | disclosed |
| EP-2134682-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | Sanofi-Aventis (FR) | 2009-12-23 | — | — | EP | disclosed |
| WO-2009000411-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000411-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF 2H-INDAZOLES | SANOFI-AVENTIS (FR) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008125207-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008125207-A1 | A TRANSITION METAL CATALYZED SYNTHESIS OF N-AMINOINDOLES | SANOFI-AVENTIS (FR) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168429-A1 | Transition metal catalyzed synthesis of N-aminoindoles | NAT1, H1-3, H1-2 | MYC 3338/4885TSHR 504/4885SMN1; SMN2 4005/4885 |
| US-20100234601-A1 | Transition metal catalyzed synthesis of 2H-indazoles | H1-3, H1-2, H1-4 | MYC 2523/4885TSHR 1297/4885SMN1; SMN2 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.